معرفی یک مورد بیمار مبتلا به کارسینوم نورواندوکرین نازوفارنکس
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Abstract:
Introduction: Neuroendocrine carcinoma is one of the neoplasms of neuroendocrine system which involves organs sparing of APUD cells. The most common sites of this carcinoma are gastrointestinal and pulmonary system. From a histologic standpoint, these tumors are reactive to silver stains and specific markers like NSE(Neuron Specific Enolase), synaptophysin, and chromogranin A. Case Report: A 74-year-old woman with a complaint of 6-month nasal stuffiness, epistaxis, anosmia, and hearing loss was referred to the hospital. In her nasal examination, a vascular polypoid mass in nasopharynx was noticed. CT-scan showed a homogeneous, isodense mass in nasopharynx without bony erosion. Conclusion: After confirming the diagnosis of carcinoid tumor using specific markers and special stains, there are some factors to predict its malignancy. Systemic chemotherapy(esp. cisplatin & etuposide) is effective to treat malignant neuroendocrine tumors especially aggressive variants. Radiotherapy has palliative effect.
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Journal title
volume 13 issue 53
pages 169- 175
publication date 2007-01
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